Pathogenic Intestinal Bacteria Enhance Prostate Cancer Development via Systemic Activation of Immune Cells in Mice

Pathogenic Intestinal Bacteria Enhance Prostate Cancer Development via Systemic Activation of Immune Cells in Mice

A role for microbes has been suspected in prostate cancer but difficult to confirm in human patients. We show here that a gastrointestinal (GI) tract bacterial infection is sufficient to enhance prostate intraepithelial neoplasia (PIN) and microinvasive carcinoma in a mouse model. We found that anim...

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Bibliographic Details
Main Authors: Poutahidis, Theofilos, Cappelle, Kelsey, Levkovich, Tatiana, Lee, Chung-Wei, Doulberis, Michael, Ge, Zhongming, Fox, James G., Horwitz, Bruce H., Erdman, Susan E.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Public Library of Science 2013
Online Access:http://hdl.handle.net/1721.1/81231
https://orcid.org/0000-0001-9307-6116

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http://hdl.handle.net/1721.1/81231
https://orcid.org/0000-0001-9307-6116

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