Loss of a Conserved tRNA Anticodon Modification Perturbs Cellular Signaling

Transfer RNA (tRNA) modifications enhance the efficiency, specificity and fidelity of translation in all organisms. The anticodon modification mcm[superscript 5]s[superscript 2]U[superscript 34] is required for normal growth and stress resistance in yeast; mutants lacking this modification have nume...

ver descrição completa

Detalhes bibliográficos
Principais autores: Zinshteyn, Boris, Gilbert, Wendy
Outros Autores: Massachusetts Institute of Technology. Department of Biology
Formato: Artigo
Idioma:en_US
Publicado em: Public Library of Science 2013
Acesso em linha:http://hdl.handle.net/1721.1/81248
https://orcid.org/0000-0003-2807-9657