Genome-wide single-cell-level screen for protein abundance and localization changes in response to DNA damage in S. cerevisiae

An effective response to DNA damaging agents involves modulating numerous facets of cellular homeostasis in addition to DNA repair and cell-cycle checkpoint pathways. Fluorescence microscopy-based imaging offers the opportunity to simultaneously interrogate changes in both protein level and subcellu...

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Bibliographic Details
Main Authors: Mazumder, Aprotim, Bathe, Mark, Samson, Leona D., Pesudo Quiros, Laia, McRee, Siobhan K.
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Language:en_US
Published: Oxford University Press 2013
Online Access:http://hdl.handle.net/1721.1/81341
https://orcid.org/0000-0002-6199-6855
https://orcid.org/0000-0002-7112-1454