Amplified stretch of bottlebrush-coated DNA in nanofluidic channels

The effect of a cationic-neutral diblock polypeptide on the conformation of single DNA molecules confined in rectangular nanochannels is investigated with fluorescence microscopy. An enhanced stretch along the channel is observed with increased binding of the cationic block of the polypeptide to DNA...

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Bibliographic Details
Main Authors: Doyle, Patrick S., Zhang, Ce, Hernandez-Garcia, Armando, Jiang, Kai, Gong, Zongying, Guttula, Durgarao, Ng, Siow Yee, Malar, Piravi P., van Kan, Jeroen A., Dai, Liang, de Vries, Renko, van der Maarel, Johan R. C.
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Oxford University Press 2013
Online Access:http://hdl.handle.net/1721.1/81342