A Bulky Biaryl Phosphine Ligand Allows for Palladium-Catalyzed Amidation of Five-Membered Heterocycles as Electrophiles
The incredible bulk: The first palladium-catalyzed amidation of five-membered heterocyclic bromides with multiple heteroatoms was achieved using the Pd/1 catalyst system. N-Arylated imidazoles, pyrazoles, thiazoles, pyrroles, and thiophenes were synthesized in moderate to excellent yield. Experiment...
| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | en_US |
| Publicado em: |
Wiley Blackwell
2013
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| Acesso em linha: | http://hdl.handle.net/1721.1/81944 https://orcid.org/0000-0003-3875-4775 |