Accelerating Palladium-Catalyzed C-F Bond Formation: Use of a Microflow Packed-Bed Reactor

A flow process for Pd-catalyzed C-F bond formation is described. A microreactor with a packed-bed design allows for easy handling of large quantities of insoluble CsF with precise control over reaction times, efficient mixing, and the ability to safely handle elevated temperatures and pressures. A v...

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Detalhes bibliográficos
Principais autores: Maimone, Thomas, Noel, Timothy, Buchwald, Stephen Leffler
Outros Autores: Massachusetts Institute of Technology. Department of Chemistry
Formato: Artigo
Idioma:en_US
Publicado em: Wiley Blackwell 2013
Acesso em linha:http://hdl.handle.net/1721.1/81946
https://orcid.org/0000-0002-3107-6927
https://orcid.org/0000-0003-3875-4775