Pd-Catalyzed Synthesis of Ar-SCF3 Compounds under Mild Conditions

Good to excellent yields of aryl trifluoromethyl sulfides, which are an important class of compounds in both the pharmaceutical and agrochemical areas, can be achieved under mild conditions by the Pd-catalyzed reaction of aryl bromides with a trifluoromethylthiolate nucleophile (see scheme).

Bibliographic Details
Main Authors: Teverovskiy, Georgiy, Surry, David S., Buchwald, Stephen Leffler
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: Wiley Blackwell 2013
Online Access:http://hdl.handle.net/1721.1/81964
https://orcid.org/0000-0003-3875-4775