Pd-Catalyzed Synthesis of Ar-SCF3 Compounds under Mild Conditions
Good to excellent yields of aryl trifluoromethyl sulfides, which are an important class of compounds in both the pharmaceutical and agrochemical areas, can be achieved under mild conditions by the Pd-catalyzed reaction of aryl bromides with a trifluoromethylthiolate nucleophile (see scheme).
| Main Authors: | , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Wiley Blackwell
2013
|
| Online Access: | http://hdl.handle.net/1721.1/81964 https://orcid.org/0000-0003-3875-4775 |
| _version_ | 1811073408558956544 |
|---|---|
| author | Teverovskiy, Georgiy Surry, David S. Buchwald, Stephen Leffler |
| author2 | Massachusetts Institute of Technology. Department of Chemistry |
| author_facet | Massachusetts Institute of Technology. Department of Chemistry Teverovskiy, Georgiy Surry, David S. Buchwald, Stephen Leffler |
| author_sort | Teverovskiy, Georgiy |
| collection | MIT |
| description | Good to excellent yields of aryl trifluoromethyl sulfides, which are an important class of compounds in both the pharmaceutical and agrochemical areas, can be achieved under mild conditions by the Pd-catalyzed reaction of aryl bromides with a trifluoromethylthiolate nucleophile (see scheme). |
| first_indexed | 2024-09-23T09:32:36Z |
| format | Article |
| id | mit-1721.1/81964 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T09:32:36Z |
| publishDate | 2013 |
| publisher | Wiley Blackwell |
| record_format | dspace |
| spelling | mit-1721.1/819642022-09-26T12:08:32Z Pd-Catalyzed Synthesis of Ar-SCF3 Compounds under Mild Conditions Teverovskiy, Georgiy Surry, David S. Buchwald, Stephen Leffler Massachusetts Institute of Technology. Department of Chemistry Teverovskiy, Georgiy Surry, David S. Buchwald, Stephen Leffler Good to excellent yields of aryl trifluoromethyl sulfides, which are an important class of compounds in both the pharmaceutical and agrochemical areas, can be achieved under mild conditions by the Pd-catalyzed reaction of aryl bromides with a trifluoromethylthiolate nucleophile (see scheme). National Institutes of Health (U.S.) (GM-58160) American Society for Engineering Education. National Defense Science and Engineering Graduate Fellowship (32 CFR 168a) National Science Foundation (U.S.) (CHE-980861) 2013-11-04T14:55:31Z 2013-11-04T14:55:31Z 2011-06 2011-04 Article http://purl.org/eprint/type/JournalArticle 14337851 1521-3773 http://hdl.handle.net/1721.1/81964 Teverovskiy, Georgiy, David S. Surry, and Stephen L. Buchwald. “Pd-Catalyzed Synthesis of Ar-SCF3 Compounds under Mild Conditions.” Angewandte Chemie International Edition 50, no. 32 (August 1, 2011): 7312-7314. https://orcid.org/0000-0003-3875-4775 en_US http://dx.doi.org/10.1002/anie.201102543 Angewandte Chemie International Edition Creative Commons Attribution-Noncommercial-Share Alike 3.0 http://creativecommons.org/licenses/by-nc-sa/3.0/ application/pdf Wiley Blackwell PMC |
| spellingShingle | Teverovskiy, Georgiy Surry, David S. Buchwald, Stephen Leffler Pd-Catalyzed Synthesis of Ar-SCF3 Compounds under Mild Conditions |
| title | Pd-Catalyzed Synthesis of Ar-SCF3 Compounds under Mild Conditions |
| title_full | Pd-Catalyzed Synthesis of Ar-SCF3 Compounds under Mild Conditions |
| title_fullStr | Pd-Catalyzed Synthesis of Ar-SCF3 Compounds under Mild Conditions |
| title_full_unstemmed | Pd-Catalyzed Synthesis of Ar-SCF3 Compounds under Mild Conditions |
| title_short | Pd-Catalyzed Synthesis of Ar-SCF3 Compounds under Mild Conditions |
| title_sort | pd catalyzed synthesis of ar scf3 compounds under mild conditions |
| url | http://hdl.handle.net/1721.1/81964 https://orcid.org/0000-0003-3875-4775 |
| work_keys_str_mv | AT teverovskiygeorgiy pdcatalyzedsynthesisofarscf3compoundsundermildconditions AT surrydavids pdcatalyzedsynthesisofarscf3compoundsundermildconditions AT buchwaldstephenleffler pdcatalyzedsynthesisofarscf3compoundsundermildconditions |