Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner

Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner

The blood vessels of cancerous tumours are leaky and poorly organized. This can increase the interstitial fluid pressure inside tumours and reduce blood supply to them, which impairs drug delivery. Anti-angiogenic therapies—which ‘normalize’ the abnormal blood vessels in tumours by making them less...

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Bibliographic Details
Main Authors: Chauhan, Vikash P., Stylianopoulos, Triantafyllos, Chen, Ou, Kamoun, Walid S., Bawendi, Moungi G., Fukumura, Dai, Jain, Rakesh K., Martin, John Daniel, Popovic, Zoran
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2013
Online Access:http://hdl.handle.net/1721.1/81989
https://orcid.org/0000-0003-2220-4365

Internet

http://hdl.handle.net/1721.1/81989
https://orcid.org/0000-0003-2220-4365

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