Mechanistic studies of an unprecedented enzyme-catalysed 1,2-phosphono-migration reaction
(S)-2-hydroxypropylphosphonate ((S)-2-HPP) epoxidase (HppE) is a mononuclear non-haem-iron-dependent enzyme1, 2, 3 responsible for the final step in the biosynthesis of the clinically useful antibiotic fosfomycin4. Enzymes of this class typically catalyse oxygenation reactions that proceed via the f...
Main Authors: | , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2013
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Online Access: | http://hdl.handle.net/1721.1/82019 https://orcid.org/0000-0001-5486-2755 |