Physical Basis of Metal-Binding Specificity in Escherichia coli NikR

Physical Basis of Metal-Binding Specificity in Escherichia coli NikR

In Escherichia coli and other bacteria, nickel uptake is regulated by the transcription factor NikR. Nickel binding at high-affinity sites in E. coli NikR (EcNikR) facilitates EcNikR binding to the nik operon, where it then suppresses transcription of genes encoding the nickel uptake transporter, Ni...

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Bibliographic Details
Main Authors: Phillips, Christine M., Nerenberg, Paul S., Drennan, Catherine L, Stultz, Collin M
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2013
Online Access:http://hdl.handle.net/1721.1/82042
https://orcid.org/0000-0001-5486-2755
https://orcid.org/0000-0002-3415-242X

Internet

http://hdl.handle.net/1721.1/82042
https://orcid.org/0000-0001-5486-2755
https://orcid.org/0000-0002-3415-242X

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