Equilibration of Tyrosyl Radicals (Y[• over 356], Y[• over 731], Y[• over 730]) in the Radical Propagation Pathway of the Escherichia coli Class Ia Ribonucleotide Reductase

Escherichia coli ribonucleotide reductase is an α2β2 complex that catalyzes the conversion of nucleotides to deoxynucleotides using a diferric tyrosyl radical (Y[• over 122]) cofactor in β2 to initiate catalysis in α2. Each turnover requires reversible long-range proton-coupled electron transfer (PC...

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Main Authors: Yokoyama, Kenichi, Smith, Albert A., Stubbe, JoAnne, Corzilius, Bjorn, Griffin, Robert Guy
其他作者: Massachusetts Institute of Technology. Department of Biology
格式: 文件
语言:en_US
出版: American Chemical Society (ACS) 2013
在线阅读:http://hdl.handle.net/1721.1/82079
https://orcid.org/0000-0003-1589-832X
https://orcid.org/0000-0001-8076-4489