On the Synergism Between H[subscript 2]O and a Tetrahydropyran Template in the Regioselective Cyclization of an Epoxy Alcohol

A regioselective epoxy alcohol cyclization promoted by the combination of neutral water and a tetrahydropyran template was investigated through a series of mechanistic experiments carried out on an epoxy alcohol containing a tetrahydropyran ring (1a) and its carbocyclic congener (1b). In contrast to...

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Bibliographic Details
Main Authors: Byers, Jeffery A., Jamison, Timothy F.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2013
Online Access:http://hdl.handle.net/1721.1/82097
https://orcid.org/0000-0002-8601-7799