Nanowire-Mediated Delivery Enables Functional Interrogation of Primary Immune Cells: Application to the Analysis of Chronic Lymphocytic Leukemia

Nanowire-Mediated Delivery Enables Functional Interrogation of Primary Immune Cells: Application to the Analysis of Chronic Lymphocytic Leukemia

A circuit level understanding of immune cells and hematological cancers has been severely impeded by a lack of techniques that enable intracellular perturbation without significantly altering cell viability and function. Here, we demonstrate that vertical silicon nanowires (NWs) enable gene-specific...

Full description

Bibliographic Details
Main Authors: Shalek, Alex K., Gaublomme, Jellert T., Wang, Lili, Yosef, Nir, Chevrier, Nicolas, Andersen, Mette S., Robinson, Jacob T., Pochet, Nathalie, Neuberg, Donna S., Gertner, Rona S., Amit, Ido, Brown, Jennifer R., Hacohen, Nir, Regev, Aviv, Wu, Catherine J., Park, Hongkun
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2013
Online Access:http://hdl.handle.net/1721.1/82108
https://orcid.org/0000-0001-8567-2049

Internet

http://hdl.handle.net/1721.1/82108
https://orcid.org/0000-0001-8567-2049

Similar Items