Nanowire-Mediated Delivery Enables Functional Interrogation of Primary Immune Cells: Application to the Analysis of Chronic Lymphocytic Leukemia
A circuit level understanding of immune cells and hematological cancers has been severely impeded by a lack of techniques that enable intracellular perturbation without significantly altering cell viability and function. Here, we demonstrate that vertical silicon nanowires (NWs) enable gene-specific...
Principais autores: | Shalek, Alex K., Gaublomme, Jellert T., Wang, Lili, Yosef, Nir, Chevrier, Nicolas, Andersen, Mette S., Robinson, Jacob T., Pochet, Nathalie, Neuberg, Donna S., Gertner, Rona S., Amit, Ido, Brown, Jennifer R., Hacohen, Nir, Regev, Aviv, Wu, Catherine J., Park, Hongkun |
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Outros Autores: | Massachusetts Institute of Technology. Department of Biology |
Formato: | Artigo |
Idioma: | en_US |
Publicado em: |
American Chemical Society (ACS)
2013
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Acesso em linha: | http://hdl.handle.net/1721.1/82108 https://orcid.org/0000-0001-8567-2049 |
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