Nanowire-Mediated Delivery Enables Functional Interrogation of Primary Immune Cells: Application to the Analysis of Chronic Lymphocytic Leukemia

A circuit level understanding of immune cells and hematological cancers has been severely impeded by a lack of techniques that enable intracellular perturbation without significantly altering cell viability and function. Here, we demonstrate that vertical silicon nanowires (NWs) enable gene-specific...

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Detalhes bibliográficos
Principais autores: Shalek, Alex K., Gaublomme, Jellert T., Wang, Lili, Yosef, Nir, Chevrier, Nicolas, Andersen, Mette S., Robinson, Jacob T., Pochet, Nathalie, Neuberg, Donna S., Gertner, Rona S., Amit, Ido, Brown, Jennifer R., Hacohen, Nir, Regev, Aviv, Wu, Catherine J., Park, Hongkun
Outros Autores: Massachusetts Institute of Technology. Department of Biology
Formato: Artigo
Idioma:en_US
Publicado em: American Chemical Society (ACS) 2013
Acesso em linha:http://hdl.handle.net/1721.1/82108
https://orcid.org/0000-0001-8567-2049

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