Water Overcomes Methyl Group Directing Effects in Epoxide-Opening Cascades
Water is an effective promoter of the endo-selective opening of trisubstituted epoxides, enabling related cascades leading to a variety of substituted ladder polyether structures. When used in conjunction with a tetrahydropyran-templated nucleophile, water can overcome the powerful electronic direct...
Main Authors: | Morten, Christopher J., Jamison, Timothy F. |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society (ACS)
2013
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Online Access: | http://hdl.handle.net/1721.1/82116 https://orcid.org/0000-0002-8601-7799 |
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