A reductive coupling strategy towards ripostatin A

Synthetic studies on the antibiotic natural product ripostatin A have been carried out with the aim to construct the C9−C10 bond by a nickel(0)-catalyzed coupling reaction of an enyne and an epoxide, followed by rearrangement of the resulting dienylcyclopropane intermediate to afford the skipped 1,4...

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Bibliographic Details
Main Authors: Schleicher, Kristin D., Jamison, Timothy F.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: Beilstein-Institut 2013
Online Access:http://hdl.handle.net/1721.1/82124
https://orcid.org/0000-0002-8601-7799