Redox-Linked Structural Changes in Ribonucleotide Reductase

Ribonucleotide reductase (RNR) catalyzes the reduction of ribonucleotides to deoxyribonucleotides. Class I RNRs are composed of two homodimeric proteins, α2 and β2. The class Ia E. coli β2 contains dinuclear, antiferromagnetically coupled iron centers and one tyrosyl free radical, Y122•/β2. Y122• ac...

Full description

Bibliographic Details
Main Authors: Offenbacher, Adam R., Vassiliev, I. R., Barry, Bridgette A., Stubbe, JoAnne, Seyedsayamdost, Mohammad R.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2013
Online Access:http://hdl.handle.net/1721.1/82563
https://orcid.org/0000-0001-8076-4489