Redox-Linked Structural Changes in Ribonucleotide Reductase
Ribonucleotide reductase (RNR) catalyzes the reduction of ribonucleotides to deoxyribonucleotides. Class I RNRs are composed of two homodimeric proteins, α2 and β2. The class Ia E. coli β2 contains dinuclear, antiferromagnetically coupled iron centers and one tyrosyl free radical, Y122•/β2. Y122• ac...
Main Authors: | Offenbacher, Adam R., Vassiliev, I. R., Barry, Bridgette A., Stubbe, JoAnne, Seyedsayamdost, Mohammad R. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society (ACS)
2013
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Online Access: | http://hdl.handle.net/1721.1/82563 https://orcid.org/0000-0001-8076-4489 |
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