Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels

Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels

Cancer and stromal cells actively exert physical forces (solid stress) to compress tumour blood vessels, thus reducing vascular perfusion. Tumour interstitial matrix also contributes to solid stress, with hyaluronan implicated as the primary matrix molecule responsible for vessel compression because...

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Những tác giả chính:	Chauhan, Vikash P., Liu, Hao, Lacorre, Delphine A., Jain, Saloni R., Kozin, Sergey V., Stylianopoulos, Triantafyllos, Mousa, Ahmed S., Han, Xiaoxing, Adstamongkonkul, Pichet, Huang, Peigen, Bawendi, Moungi G., Boucher, Yves, Jain, Rakesh K., Martin, John Daniel, Popovic, Zoran
Tác giả khác:	Massachusetts Institute of Technology. Department of Chemical Engineering
Định dạng:	Bài viết
Ngôn ngữ:	en_US
Được phát hành:	Nature Publishing Group 2013
Truy cập trực tuyến:	http://hdl.handle.net/1721.1/82573 https://orcid.org/0000-0003-2220-4365

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