Human Defensin 5 Disulfide Array Mutants: Disulfide Bond Deletion Attenuates Antibacterial Activity against Staphylococcus aureus

Human α-defensin 5 (HD5, HD5[subscript ox] to specify the oxidized and disulfide linked form) is a 32-residue cysteine-rich host-defense peptide, expressed and released by small intestinal Paneth cells, that exhibits antibacterial activity against a number of Gram-negative and -positive bacterial st...

Full description

Bibliographic Details
Main Authors: Wanniarachchi, Yoshitha A., Kaczmarek, Piotr, Wan, Andrea, Nolan, Elizabeth M.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society 2013
Online Access:http://hdl.handle.net/1721.1/82575
https://orcid.org/0000-0002-6153-8803