Human Defensin 5 Disulfide Array Mutants: Disulfide Bond Deletion Attenuates Antibacterial Activity against Staphylococcus aureus
Human α-defensin 5 (HD5, HD5[subscript ox] to specify the oxidized and disulfide linked form) is a 32-residue cysteine-rich host-defense peptide, expressed and released by small intestinal Paneth cells, that exhibits antibacterial activity against a number of Gram-negative and -positive bacterial st...
Main Authors: | Wanniarachchi, Yoshitha A., Kaczmarek, Piotr, Wan, Andrea, Nolan, Elizabeth M. |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society
2013
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Online Access: | http://hdl.handle.net/1721.1/82575 https://orcid.org/0000-0002-6153-8803 |
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