Assessment of heterologous butyrate and butanol pathway activity by measurement of intracellular pathway intermediates in recombinant Escherichia coli

In clostridia, n-butanol production from carbohydrates at yields of up to 76% of the theoretical maximum and at titers of up to 13 g/L has been reported. However, in Escherichia coli, several groups have reported butyric acid or butanol production from recombinant expression of clostridial genes, at...

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Bibliographic Details
Main Authors: Fischer, Curt R., Tseng, Hsien-Chung, Tai, Mitchell, Stephanopoulos, Gregory, Prather, Kristala L. Jones
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Springer-Verlag 2013
Online Access:http://hdl.handle.net/1721.1/82623
https://orcid.org/0000-0003-0437-3157
https://orcid.org/0000-0001-6909-4568