Aneuploidy Drives Genomic Instability in Yeast

Aneuploidy Drives Genomic Instability in Yeast

Aneuploidy decreases cellular fitness, yet it is also associated with cancer, a disease of enhanced proliferative capacity. To investigate one mechanism by which aneuploidy could contribute to tumorigenesis, we examined the effects of aneuploidy on genomic stability. We analyzed 13 budding yeast str...

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Bibliographic Details
Main Authors: Sheltzer, Jason Meyer, Blank, Heidi Marie, Pfau, Sarah Jeanne, Tange, Yoshie, George, Benson M., Humpton, Timothy J., Brito, Ilana Lauren, Hiraoka, Yasushi, Niwa, Osami, Amon, Angelika B
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Association for the Advancement of Science 2013
Online Access:http://hdl.handle.net/1721.1/82910
https://orcid.org/0000-0002-4698-2746
https://orcid.org/0000-0001-9837-0314
https://orcid.org/0000-0003-1381-1323

Internet

http://hdl.handle.net/1721.1/82910
https://orcid.org/0000-0002-4698-2746
https://orcid.org/0000-0001-9837-0314
https://orcid.org/0000-0003-1381-1323

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