Interplay between chromatin state, regulator binding, and regulatory motifs in six human cell types

The regions bound by sequence-specific transcription factors can be highly variable across different cell types despite the static nature of the underlying genome sequence. This has been partly attributed to changes in chromatin accessibility, but a systematic picture has been hindered by the lack o...

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Bibliographic Details
Main Authors: Kellis, Manolis, Ernst, Jason
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Cold Spring Harbor Laboratory Press 2013
Online Access:http://hdl.handle.net/1721.1/82918