Hypoxia promotes liver stage malaria infection in primary human hepatocytes in vitro

Homeostasis of mammalian cell function strictly depends on balancing oxygen exposure to maintain energy metabolism without producing excessive reactive oxygen species. In vivo, cells in different tissues are exposed to a wide range of oxygen concentrations, and yet in vitro models almost exclusively...

Full description

Bibliographic Details
Main Authors: Ng, Shengyong, March-Riera, Sandra, Galstian, Ani, Hanson, Kirsten, Carvalho, Tania, Mota, Maria M., Bhatia, Sangeeta N
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Company of Biologists 2013
Online Access:http://hdl.handle.net/1721.1/82922
https://orcid.org/0000-0002-1293-2097
https://orcid.org/0000-0001-8863-7310