Eukaryotic Origin-Dependent DNA Replication In Vitro Reveals Sequential Action of DDK and S-CDK Kinases

Eukaryotic Origin-Dependent DNA Replication In Vitro Reveals Sequential Action of DDK and S-CDK Kinases

Proper eukaryotic DNA replication requires temporal separation of helicase loading from helicase activation and replisome assembly. Using an in vitro assay for eukaryotic origin-dependent replication initiation, we investigated the control of these events. After helicase loading, we found that the D...

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Bibliographic Details
Main Authors: Heller, Ryan C., Kang, Sukhyun, Lam, Wendy M., Chen, Shuyan, Chan, Clara Sophia, Bell, Stephen P
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier B.V. 2013
Online Access:http://hdl.handle.net/1721.1/82945
https://orcid.org/0000-0002-2876-610X

Internet

http://hdl.handle.net/1721.1/82945
https://orcid.org/0000-0002-2876-610X

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