The Inside-Out Mechanism of Dicers from Budding Yeasts
The Dicer ribonuclease III (RNase III) enzymes process long double-stranded RNA (dsRNA) into small interfering RNAs (siRNAs) that direct RNA interference. Here, we describe the structure and activity of a catalytically active fragment of Kluyveromyces polysporus Dcr1, which represents the noncanonic...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Elsevier B.V.
2013
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| Online Access: | http://hdl.handle.net/1721.1/83086 https://orcid.org/0000-0002-3872-2856 |