Single-Molecule Protein Unfolding and Translocation by an ATP-Fueled Proteolytic Machine

Single-Molecule Protein Unfolding and Translocation by an ATP-Fueled Proteolytic Machine

All cells employ ATP-powered proteases for protein-quality control and regulation. In the ClpXP protease, ClpX is a AAA+ machine that recognizes specific protein substrates, unfolds these molecules, and then translocates the denatured polypeptide through a central pore and into ClpP for degradation....

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Bibliographic Details
Main Authors: Aubin-Tam, Marie-Eve, Olivares, Adrian O., Baker, Tania, Lang, Matthew J., Sauer, Robert T., Sauer, Robert T
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier B.V. 2013
Online Access:http://hdl.handle.net/1721.1/83088
https://orcid.org/0000-0002-4614-251X
https://orcid.org/0000-0002-1719-5399

Internet

http://hdl.handle.net/1721.1/83088
https://orcid.org/0000-0002-4614-251X
https://orcid.org/0000-0002-1719-5399

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