Evolutionary remodeling of global regulatory networks during long-term bacterial adaptation to human hosts

The genetic basis of bacterial adaptation to a natural environment has been investigated in a highly successful Pseudomonas aeruginosa lineage (DK2) that evolved within the airways of patients with cystic fibrosis (CF) for more than 35 y. During evolution in the CF airways, the DK2 lineage underwent...

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Bibliographic Details
Main Authors: Yang, Lei, Damkiaer, Soren, Molin, Soren, Jelsbak, Lars
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2013
Online Access:http://hdl.handle.net/1721.1/83352