X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification

Arylsulfatases require a maturating enzyme to perform a co- or posttranslational modification to form a catalytically essential formylglycine (FGly) residue. In organisms that live aerobically, molecular oxygen is used enzymatically to oxidize cysteine to FGly. Under anaerobic conditions, S-adenosyl...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Goldman, Peter J., McLaughlin, Martin I., Drennan, Catherine L., Grove, Tyler L., Sites, Lauren A., Booker, Squire J.
مؤلفون آخرون: Massachusetts Institute of Technology. Department of Biology
التنسيق: مقال
اللغة:en_US
منشور في: National Academy of Sciences (U.S.) 2013
الوصول للمادة أونلاين:http://hdl.handle.net/1721.1/83377
https://orcid.org/0000-0001-5486-2755