Distinct quaternary structures of the AAA+ Lon protease control substrate degradation

Lon is an ATPase associated with cellular activities (AAA+) protease that controls cell division in response to stress and also degrades misfolded and damaged proteins. Subunits of Lon are known to assemble into ring-shaped homohexamers that enclose an internal degradation chamber. Here, we demonstr...

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Bibliographic Details
Main Authors: Vieux (Kloss), Ellen, Wohlever, Matthew Lee, Chen, James Z., Baker, Tania, Sauer, Robert T
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2013
Online Access:http://hdl.handle.net/1721.1/83385
https://orcid.org/0000-0002-1719-5399