Fitness Trade-offs Restrict the Evolution of Resistance to Amphotericin B
The evolution of drug resistance in microbial pathogens provides a paradigm for investigating evolutionary dynamics with important consequences for human health. Candida albicans, the leading fungal pathogen of humans, rapidly evolves resistance to two major antifungal classes, the triazoles and ech...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Public Library of Science
2013
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| Online Access: | http://hdl.handle.net/1721.1/83390 https://orcid.org/0000-0003-1307-882X |