Antagonism between Ena/VASP Proteins and Actin Filament Capping Regulates Fibroblast Motility

Antagonism between Ena/VASP Proteins and Actin Filament Capping Regulates Fibroblast Motility

Cell motility requires lamellipodial protrusion, a process driven by actin polymerization. Ena/VASP proteins accumulate in protruding lamellipodia and promote the rapid actin-driven motility of the pathogen Listeria. In contrast, Ena/VASP negatively regulate cell translocation. To resolve this parad...

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Bibliographic Details
Main Authors: Bear, James E., Svitkina, Tatyana M., Krause, Matthias, Schafer, Dorothy A., Loureiro, Joseph J., Strasser, Geraldine A., Maly, Ivan V., Chaga, Oleg Y., Cooper, John A., Borisy, Gary G., Gertler, Frank
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/83477
https://orcid.org/0000-0003-3214-4554

Internet

http://hdl.handle.net/1721.1/83477
https://orcid.org/0000-0003-3214-4554

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