Critical Role of Ena/VASP Proteins for Filopodia Formation in Neurons and in Function Downstream of Netrin-1

Ena/VASP proteins play important roles in axon outgrowth and guidance. Ena/VASP activity regulates the assembly and geometry of actin networks within fibroblast lamellipodia. In growth cones, Ena/VASP proteins are concentrated at filopodia tips, yet their role in growth cone responses to guidance si...

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Bibliographic Details
Main Authors: Lebrand, Cecile, Lanier, Lorene M., Krause, Matthias, Svitkina, Tatyana M., Borisy, Gary G., Dent, Erik W., Strasser, Geraldine A., Gertler, Frank
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/83481
https://orcid.org/0000-0001-8525-7136
https://orcid.org/0000-0003-3214-4554