Critical Role of Ena/VASP Proteins for Filopodia Formation in Neurons and in Function Downstream of Netrin-1
Ena/VASP proteins play important roles in axon outgrowth and guidance. Ena/VASP activity regulates the assembly and geometry of actin networks within fibroblast lamellipodia. In growth cones, Ena/VASP proteins are concentrated at filopodia tips, yet their role in growth cone responses to guidance si...
Main Authors: | Lebrand, Cecile, Lanier, Lorene M., Krause, Matthias, Svitkina, Tatyana M., Borisy, Gary G., Dent, Erik W., Strasser, Geraldine A., Gertler, Frank |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2014
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Online Access: | http://hdl.handle.net/1721.1/83481 https://orcid.org/0000-0001-8525-7136 https://orcid.org/0000-0003-3214-4554 |
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