Negative Regulation of Fibroblast Motility by Ena/VASP Proteins

Ena/VASP proteins have been implicated in cell motility through regulation of the actin cytoskeleton and are found at focal adhesions and the leading edge. Using overexpression, loss-of-function, and inhibitory approaches, we find that Ena/VASP proteins negatively regulate fibroblast motility. A dos...

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Bibliographic Details
Main Authors: Libova, Irina, Bear, James E., Loureiro, Joseph J., Gertler, Frank, Fassler, Reinhard, Wehland, Jurgen
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/83484
https://orcid.org/0000-0003-3214-4554