Negative Regulation of Fibroblast Motility by Ena/VASP Proteins
Ena/VASP proteins have been implicated in cell motility through regulation of the actin cytoskeleton and are found at focal adhesions and the leading edge. Using overexpression, loss-of-function, and inhibitory approaches, we find that Ena/VASP proteins negatively regulate fibroblast motility. A dos...
Main Authors: | Libova, Irina, Bear, James E., Loureiro, Joseph J., Gertler, Frank, Fassler, Reinhard, Wehland, Jurgen |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2014
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Online Access: | http://hdl.handle.net/1721.1/83484 https://orcid.org/0000-0003-3214-4554 |
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