RIAM, an Ena/VASP and Profilin Ligand, Interacts with Rap1-GTP and Mediates Rap1-Induced Adhesion

RIAM, an Ena/VASP and Profilin Ligand, Interacts with Rap1-GTP and Mediates Rap1-Induced Adhesion

The small GTPase Rap1 induces integrin-mediated adhesion and changes in the actin cytoskeleton. The mechanisms that mediate these effects of Rap1 are poorly understood. We have identified RIAM as a Rap1-GTP-interacting adaptor molecule. RIAM defines a family of adaptor molecules that contain a RA-li...

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Bibliographic Details
Main Authors: Lafuente, Esther M., Krause, Matthias, Carman, Christopher V., Freeman, Gordon J., Berezovskaya, Alla, Constantine, Erica, Springer, Timothy A., Boussiotis, Vassiliki A., Gertler, Frank, van Puijenbroek, Andre A.F.L.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/83508
https://orcid.org/0000-0003-3214-4554

Internet

http://hdl.handle.net/1721.1/83508
https://orcid.org/0000-0003-3214-4554

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