Transcriptional Amplification in Tumor Cells with Elevated c-Myc

Transcriptional Amplification in Tumor Cells with Elevated c-Myc

Elevated expression of the c-Myc transcription factor occurs frequently in human cancers and is associated with tumor aggression and poor clinical outcome. The effect of high levels of c-Myc on global gene regulation is poorly understood but is widely thought to involve newly activated or repressed...

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Bibliographic Details
Main Authors: Lin, Charles Y., Loven, Jakob, Rahl, Peter B., Paranal, Ronald M., Burge, Christopher B., Bradner, James E., Lee, Tong Ihn, Young, Richard A.
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: Elsevier B.V. 2014
Online Access:http://hdl.handle.net/1721.1/83614
https://orcid.org/0000-0001-8855-8647

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http://hdl.handle.net/1721.1/83614
https://orcid.org/0000-0001-8855-8647

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