Roles for transcript leaders in translation and mRNA decay revealed by transcript leader sequencing
Transcript leaders (TLs) can have profound effects on mRNA translation and stability. To map TL boundaries genome-wide, we developed TL-sequencing (TL-seq), a technique combining enzymatic capture of m[superscript 7]G-capped mRNA 5′ ends with high-throughput sequencing. TL-seq identified mRNA start...
| Autores principales: | , |
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| Formato: | Artículo |
| Lenguaje: | en_US |
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Cold Spring Harbor Laboratory Press
2014
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| Acceso en línea: | http://hdl.handle.net/1721.1/83927 https://orcid.org/0000-0003-2807-9657 |