Genetic Predisposition Directs Breast Cancer Phenotype by Dictating Progenitor Cell Fate

Genetic Predisposition Directs Breast Cancer Phenotype by Dictating Progenitor Cell Fate

Women with inherited mutations in the BRCA1 gene have increased risk of developing breast cancer but also exhibit a predisposition for the development of aggressive basal-like breast tumors. We report here that breast epithelial cells derived from patients harboring deleterious mutations in BRCA1 (B...

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Bibliográfalaš dieđut
Váldodahkkit: Proia, Theresa A., Keller, Patricia J., Klebba, Ina, Jones, Ainsley D., Sedic, Maja, Gilmore, Hannah, Tung, Nadine, Naber, Stephen P., Schnitt, Stuart, Gupta, Piyush, Kuperwasser, Charlotte, Lander, Eric Steven
Eará dahkkit: Massachusetts Institute of Technology. Department of Biology
Materiálatiipa: Artihkal
Giella:en_US
Almmustuhtton: Elsevier 2014
Liŋkkat:http://hdl.handle.net/1721.1/84488
https://orcid.org/0000-0002-9703-1780

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http://hdl.handle.net/1721.1/84488
https://orcid.org/0000-0002-9703-1780

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