Metabolic and Neuropsychiatric Effects of Calorie Restriction and Sirtuins

Most living organisms, including humans, age. Over time the ability to do physical and intellectual work deteriorates, and susceptibility to infectious, metabolic, and neurodegenerative diseases increases, which leads to general fitness decline and ultimately to death. Work in model organisms has de...

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Bibliographic Details
Main Authors: Libert, Sergiy V., Guarente, Leonard Pershing
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Annual Reviews 2014
Online Access:http://hdl.handle.net/1721.1/84495
https://orcid.org/0000-0003-4064-2510