Sirtuin deacetylases in neurodegenerative diseases of aging
Sirtuin enzymes are a family of highly conserved protein deacetylases that depend on nicotinamide adenine dinucleotide (NAD+) for their activity. There are seven sirtuins in mammals and these proteins have been linked with caloric restriction and aging by modulating energy metabolism, genomic stabil...
Main Authors: | Herskovits, A. Zara, Guarente, Leonard Pershing |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2014
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Online Access: | http://hdl.handle.net/1721.1/84499 https://orcid.org/0000-0002-6841-4539 https://orcid.org/0000-0003-4064-2510 |
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