SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin
Mesenchymal stem cells (MSCs) are multi‐potent cells that can differentiate into osteoblasts, adipocytes, chondrocytes and myocytes. This potential declines with aging. We investigated whether the sirtuin SIRT1 had a function in MSCs by creating MSC specific SIRT1 knock‐out (MSCKO) mice. Aged MSCKO...
Главные авторы: | , , , , , , , , , |
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Другие авторы: | |
Формат: | Статья |
Язык: | en_US |
Опубликовано: |
Wiley Blackwell
2014
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Online-ссылка: | http://hdl.handle.net/1721.1/84504 https://orcid.org/0000-0003-4064-2510 |