Calorie restriction and sirtuins revisited
Calorie or dietary restriction (CR) has attracted attention because it is the oldest and most robust way to extend rodent life span. The idea that the nutrient sensors, termed sirtuins, might mediate effects of CR was proposed 13 years ago and has been challenged in the intervening years. This revie...
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| Format: | Article |
| Idioma: | en_US |
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Cold Spring Harbor Laboratory Press
2014
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| Accés en línia: | http://hdl.handle.net/1721.1/84509 https://orcid.org/0000-0003-4064-2510 |