Huntington's Disease: Can Mice Lead the Way to Treatment?

Mouse models for Huntington's Disease (HD) and HD patients demonstrate motor and behavioral dysfunctions, such as progressive loss of coordination and memory, and share similar transcriptional profiles and striatal neuron atrophy. Clear differences between the mouse and human diseases include a...

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Bibliographic Details
Main Authors: Crook, Zachary Ryan, Housman, David E
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/84528
https://orcid.org/0000-0002-1142-9748
https://orcid.org/0000-0001-5016-0756