Huntington's Disease: Can Mice Lead the Way to Treatment?
Mouse models for Huntington's Disease (HD) and HD patients demonstrate motor and behavioral dysfunctions, such as progressive loss of coordination and memory, and share similar transcriptional profiles and striatal neuron atrophy. Clear differences between the mouse and human diseases include a...
Main Authors: | Crook, Zachary Ryan, Housman, David E |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2014
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Online Access: | http://hdl.handle.net/1721.1/84528 https://orcid.org/0000-0002-1142-9748 https://orcid.org/0000-0001-5016-0756 |
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