Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase

The development of animal models of lung cancer is critical to our understanding and treatment of the human disease. Conditional mouse models provide new opportunities for testing novel chemopreventatives, therapeutics and screening methods that are not possible with cultured cell lines or xenograft...

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Bibliographic Details
Main Authors: DuPage, Michel J., Brauneis, Alison L., Jacks, Tyler E.
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:en_US
Published: Nature Publishing Group 2014
Online Access:http://hdl.handle.net/1721.1/84599
https://orcid.org/0000-0001-5785-8911
https://orcid.org/0000-0002-1846-604X