A Polymorphism in npr-1 Is a Behavioral Determinant of Pathogen Susceptibility in C. elegans

The nematode Caenorhabditis elegans responds to pathogenic bacteria with conserved innate immune responses and pathogen avoidance behaviors. We investigated natural variation in C. elegans resistance to pathogen infection. With the use of quantitative genetic analysis, we determined that the pathoge...

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Bibliographic Details
Main Authors: Reddy, Kirthi C., Kim, Dennis H., Andersen, Erik C., Kruglyak, Leonid
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2014
Online Access:http://hdl.handle.net/1721.1/84622
https://orcid.org/0000-0002-4109-5152